Description
1P-LSD 150µg Blotters with AP Design 1 are an important instrument for scientific research into psychedelic substances. These blotters each contain 150 micrograms of 1P-LSD, a semi-synthetic lysergamide that is closely related to LSD and offers a unique opportunity for researchers to study the psychoactive effects of this substance. 1P-LSD is known for its potency and capacity to induce profound changes in perception, emotion and cognition. The research on 1P-LSD may provide important insights into the functioning of serotonergic systems in the brain, especially the interaction with serotonin receptors and their influence on the human experience. The study of 1P-LSD is also important for exploring the therapeutic potential of psychedelics, such as possible applications in the treatment of mental disorders such as depression, anxiety disorders and PTSD. Research into this substance can contribute to a better understanding of the neurobiological mechanisms underlying these disorders. The 150µg dosage on the blotters, characterized by the AP Design 1, ensures a standardized and accurate approach in experimental studies. This is essential for obtaining consistent and reproducible results, allowing researchers to systematically study the effects of 1P-LSD. At TRRCshop we are committed to supporting scientific research with our 1P-LSD 150µg Blotters (AP Design 1). Our focus on quality and accuracy helps researchers gain valuable insights into the action of lysergamides. By providing these blotters, we contribute to the research essential to exploring the potential of psychedelic substances for therapeutic purposes and improving our understanding of the human psyche. The unique AP Design 1 on the blotters contributes to recognisability and consistency, which is important for researchers who require accuracy in their experimental setups. These blotters are not only a tool for scientific exploration, but also a crucial component in the advancement of psychonautical studies and the development of new treatment methods for neurological and mental disorders.
Lysergic acid diethylamide (LSD) is a prototypical serotonergic psychedelic drug and the subject of many clinical investigations. In recent years, a range of lysergamides has emerged with the production of some being inspired by the existing scientific literature. Others, for example various 1‐acyl substituted lysergamides, did not exist before their appearance as research chemicals. 1‐Cylopropanoyl‐LSD (1CP‐LSD) has recently emerged as a new addition to the group of lysergamide‐based designer drugs and is believed to be psychoactive in humans. In this investigation, 1CP‐LSD was subjected to detailed analytical characterizations including various mass spectrometry (MS) platforms, gas and liquid chromatography, nuclear magnetic resonance spectroscopy, solid phase and GC condensed phase infrared spectroscopy. Analysis by GC‐MS also revealed the detection of artificially induced degradation products. Incubation of 1CP‐LSD with human serum led to the formation of LSD, indicating that it may act as a prodrug for LSD in vivo, similar to other 1‐acyl substituted lysergamides. The analysis of blotters and pellets is also included. 1CP‐LSD also induces the head‐twitch response (HTR) in C57BL/6J mice, indicating that it produces an LSD‐like behavioural profile. 1CP‐LSD induced the HTR with an ED50 = 430.0 nmol/kg which was comparable with 1P‐LSD (ED50 = 349.6 nmol/kg) investigated previously. Clinical studies are required to determine the potency and profile of effects produced by 1CP‐LSD in humans.
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