Buy 1P-LSD blotters 100mcg online

Description

IUPAC-Name: (6aR,9R)-4-propionyl-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
CAS # N/A
Other name: 1P-LSD, 1-propionyl-lysergic acid diethylamide
Appearance: 100ug Blotters (>99% purity)
Form: L-tartrate
NMR Analysis: N/A

Lysergic acid diethylamide (LSD) is a prototypical serotonergic psychedelic drug and the subject of many clinical investigations. In recent years, a range of lysergamides has emerged with the production of some being inspired by the existing scientific literature. Others, for example various 1‐acyl substituted lysergamides, did not exist before their appearance as research chemicals. 1‐Propanoyl‐LSD (1P-LSD) has recently emerged as a new addition to the group of lysergamide‐based designer drugs and is believed to be psychoactive in humans. In this investigation, 1P-LSD was subjected to detailed analytical characterizations including various mass spectrometry (MS) platforms, gas and liquid chromatography, nuclear magnetic resonance spectroscopy, solid phase and GC condensed phase infrared spectroscopy. Analysis by GC‐MS also revealed the detection of artificially induced degradation products. Incubation of 1P-LSD with human serum led to the formation of LSD, indicating that it may act as a prodrug for LSD in vivo, similar to other 1‐acyl substituted lysergamides. The analysis of blotters and pellets is also included. 1CP‐LSD also induces the head‐twitch response (HTR) in C57BL/6J mice, indicating that it produces an LSD‐like behavioural profile. 1CP‐LSD induced the HTR with an ED50 = 430.0 nmol/kg which was comparable with 1P‐LSD (ED50 = 349.6 nmol/kg) investigated previously. Clinical studies are required to determine the potency and profile of effects produced by 1P-LSD in humans.

1P-LSD Legal status Legal status AU: S8 (Controlled drug) BR: Class F2 (Prohibited psychotropics) CA: Unscheduled. DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act US: Unscheduled (may be considered illegal if sold for human consumption as an analog of LSD under the federal analogue act) UN: Unscheduled In general Unscheduled, unless that was sold for human consumption, could be sold for medical and research purposes. Identifiers IUPAC name CAS Number 2349358-81-0 check PubChem CID 119025985 ChemSpider 52085129 UNII 23R2G2G79C CompTox Dashboard (EPA) DTXSID701016895 Chemical and physical data Formula C23H29N3O2 Molar mass 379.504 g·mol−1 3D model (JSmol) Interactive image SMILES InChI 1P-LSD (1-propanoyl-lysergic acid diethylamide) is a psychedelic drug of the lysergamide class that is a derivative and functional analogue of LSD and a homologue of ALD-52. It originated in 2015 when it appeared a designer drug sold online.It was first synthesized as a legal-LSD alternative by Lizard Labs, a Netherlands based research chemical laboratory.It modifies the LSD molecule by adding a propionyl group to the nitrogen atom of LSD’s indole group. Pharmacology Like ALD-52, 1P-LSD is believed to act as a prodrug for LSD via hydrolysis of the propionyl group. When 1P-LSD is incubated in human serum, administered intravenously to rats or administered either orally or intravenously to human subjects, high levels of LSD and relatively low levels of 1P-LSD are quickly detected, demonstrating that 1P-LSD is rapidly hydrolyzed into LSD in vivo following ingestion. Indeed, following intravenous administration in humans 1P-LSD is detectable in serum for no longer than 4 hours, after which it is completely converted to LSD.These findings are supported by the similar duration and behavioral effects of 1P-LSD and LSD in both animal and human experiments. Effects 1P-LSD on blotter paper The subjective effects of 1P-LSD are not well defined in the scientific literature, although they are generally thought to be comparable to that of LSD. In a 2020 study, the qualitative effects of 1P-LSD and LSD were similar when measured using visual analog scales. Legal status As of 2015, 1P-LSD is unscheduled in the United States and Canada, but may be considered illegal if sold or used for human consumption as a structural analog of LSD under the Federal Analogue Act in the US.[10] 1P-LSD is a prohibited or controlled substance in Australia, France,Finland,Denmark, Germany, Estonia, Japan, Latvia, Norway, Romania, Sweden, Switzerland, United Kingdom, Italy,Singapore, the Czech Republic, and Croatia. 1P-LSD has been illegal in Russia since 2017 as an LSD derivative. See also 1cP-LSD 1B-LSD 1D-LSD 1V-LSD ALD-52 1cP-AL-LAD AL-LAD ETH-LAD 1P-ETH-LAD PRO-LAD LSM-775 LSZ O-Acetylpsilocin (4-AcO-DMT)